Preprint Watch

Cobalt bis(dicarbollide) is a DNA-neutral pharmacophore

Leave a Comment / chemRxiv, Normal Science /

URL https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/64660c73f2112b41e9c0f70d/original/cobalt-bis-dicarbollide-is-a-dna-neutral-pharmacophore.pdf Stage Normal Science Paradigm framing The paradigm framing of this research preprint is the well-established understanding of DNA interactions with small molecules, particularly those used as therapeutic agents. This includes the accepted mechanisms of DNA binding, such as intercalation, groove binding, and electrostatic interactions, and the typical structural characteristics of molecules that engage […]

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Metal Polluted White Dwarfs with 21 μm IR excesses from JWST/MIRI: Planets or Dust?

Leave a Comment / arXiv, Model Drift, Normal Science /

URL https://arxiv.org/pdf/2506.21224.pdf Stage Normal Science / Model Drift Paradigm framing The current paradigm is that metal pollution in white dwarfs arises from the accretion of planetary debris. This is supported by spectroscopic observations and abundance patterns consistent with rocky material. The paradigm includes theoretical models of tidal disruption events and planetary system evolution post-main sequence.

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Ecosystems as adaptive living circuits

Leave a Comment / arXiv, Model Drift /

URL https://arxiv.org/pdf/2506.22017.pdf Stage Model Drift Paradigm framing The current paradigm focuses on the non-equilibrium nature of biological systems, where the coupling to external energy sources is a fixed parameter. This preprint challenges this assumption by highlighting that energy dissipation is an adaptive, dynamic variable in living systems. Highlights This preprint identifies a limitation in existing

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scite: a smart citation index that displays the context of citations and classifies their intent using deep learning

Leave a Comment / bioRxiv, Normal Science /

URL https://web.archive.org/web/20210325215755id_/https://www.biorxiv.org/content/biorxiv/early/2021/03/16/2021.03.15.435418.full.pdf Stage Normal Science Paradigm framing Scientometrics, Bibliometrics, and Deep Learning Highlights This preprint presents scite, a novel citation indexer that uses deep learning to classify citations based on their context within citing papers. This work falls under the normal science stage of Kuhn's paradigm cycle. The preprint operates within the existing paradigms of

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Title detection: a novel approach to automatically finding retractions and other editorial notices in the scholarly literature

Leave a Comment / arXiv, Normal Science /

URL https://arxiv.org/pdf/2210.09553.pdf Stage Normal Science Paradigm framing Scholarly metadata and the need for its comprehensive accessibility. Highlights The preprint presents a novel approach to detecting editorial notices (retractions, withdrawals, errata, etc.) in scholarly literature. It acknowledges the existing paradigm of metadata indexing (Crossref, PubMed) but identifies limitations such as incompleteness and inconsistencies in publisher practices.

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AI in Universities: The Good, the Bot, and the Ugly Truths

Leave a Comment / Model Drift, Research Square /

URL https://www.researchsquare.com/article/rs-6883202/v1.pdf Stage Model Drift Paradigm framing The paradigm of the preprint revolves around the integration of Artificial Intelligence (AI) in higher education, specifically focusing on its impact on teaching, learning, and administrative functions. This encompasses the shift towards personalized learning, enhanced efficiency, and improved campus management through the use of AI-powered tools. Highlights The

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On string tension and initial temperature from transverse momentum spectra of heavy quarkonia in proton-proton collisions at the LHC

Leave a Comment / arXiv, Normal Science /

URL https://arxiv.org/pdf/2506.10702.pdf Stage Normal Science Paradigm framing The preprint operates within the Quantum Chromodynamics (QCD) paradigm, specifically focusing on heavy quarkonium production in proton-proton collisions. It utilizes established theoretical frameworks like the Schwinger mechanism and Bose-Einstein statistics to analyze experimental data. Highlights This preprint firmly falls within the normal science stage. It employs established theoretical

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MARS: Processing-In-Memory Acceleration of Raw Signal Genome Analysis Inside the Storage Subsystem

Leave a Comment / arXiv, Model Drift /

URL https://arxiv.org/pdf/2506.10931.pdf Stage Model Drift Paradigm framing The preprint operates within the established paradigm of genome analysis, which traditionally involves basecalling followed by read mapping. However, it addresses the limitations of this paradigm by proposing in-storage processing of raw signals, representing a departure from the conventional approach of relying on CPU/GPU-based acceleration of individual steps

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Laser Stabilised Ionising Transitions

Leave a Comment / arXiv, Model Drift /

URL https://arxiv.org/pdf/2506.10183.pdf Stage Model Drift Paradigm framing The dominant paradigm is the Fano model of bound-to-continuum transitions and resonant fluorescence. The preprint introduces a drift by demonstrating the emergence of a novel metastable state under resonant pumping. Highlights The preprint operates within the established paradigm of Fano's theory of bound-to-continuum transitions and utilizes resonant fluorescence

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The quantum theory of the electromagnetic field in the Weyl-Wigner representation as a local realistic model

Leave a Comment / arXiv, Model Crisis, Model Drift /

URL https://arxiv.org/pdf/2506.10023.pdf Stage Model Drift / Model Crisis Paradigm framing The preprint challenges the dominant paradigm of quantum mechanics, specifically the interpretation of entangled photon pairs and the nature of the vacuum. It sits within the paradigm of local realism but questions the completeness of Bell's theorem, thus challenging both existing paradigms simultaneously. Highlights The

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