Preprint Watch

On string tension and initial temperature from transverse momentum spectra of heavy quarkonia in proton-proton collisions at the LHC

URL https://arxiv.org/pdf/2506.10702.pdf Stage Normal Science Paradigm framing The preprint operates within the Quantum Chromodynamics (QCD) paradigm, specifically focusing on heavy quarkonium production in proton-proton collisions. It utilizes established theoretical frameworks like the Schwinger mechanism and Bose-Einstein statistics to analyze experimental data. Highlights This preprint firmly falls within the normal science stage. It employs established theoretical […]

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MARS: Processing-In-Memory Acceleration of Raw Signal Genome Analysis Inside the Storage Subsystem

URL https://arxiv.org/pdf/2506.10931.pdf Stage Model Drift Paradigm framing The preprint operates within the established paradigm of genome analysis, which traditionally involves basecalling followed by read mapping. However, it addresses the limitations of this paradigm by proposing in-storage processing of raw signals, representing a departure from the conventional approach of relying on CPU/GPU-based acceleration of individual steps

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Laser Stabilised Ionising Transitions

URL https://arxiv.org/pdf/2506.10183.pdf Stage Model Drift Paradigm framing The dominant paradigm is the Fano model of bound-to-continuum transitions and resonant fluorescence. The preprint introduces a drift by demonstrating the emergence of a novel metastable state under resonant pumping. Highlights The preprint operates within the established paradigm of Fano's theory of bound-to-continuum transitions and utilizes resonant fluorescence

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The quantum theory of the electromagnetic field in the Weyl-Wigner representation as a local realistic model

URL https://arxiv.org/pdf/2506.10023.pdf Stage Model Drift / Model Crisis Paradigm framing The preprint challenges the dominant paradigm of quantum mechanics, specifically the interpretation of entangled photon pairs and the nature of the vacuum. It sits within the paradigm of local realism but questions the completeness of Bell's theorem, thus challenging both existing paradigms simultaneously. Highlights The

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Attention-based deep learning for analysis of pathology images and gene expression data in lung squamous premalignant lesions

URL https://www.medrxiv.org/content/10.1101/2025.06.06.25328492v1.full.pdf Stage Normal Science Paradigm framing The preprint operates within the dominant paradigm of using deep learning, specifically attention-based models, for image analysis and multi-modal data integration in computational pathology. It adheres to the established practices of training and validating models on large datasets, using metrics like AUROC and AUPR for evaluation, and exploring

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Breaking Bad Molecules: Are MLLMs Ready for Structure-Level Molecular Detoxification?

URL https://arxiv.org/pdf/2506.10912.pdf Stage Normal Science Paradigm framing The preprint operates within the dominant paradigm of applying machine learning, specifically Multimodal Large Language Models (MLLMs), to address challenges in drug discovery and development. It adheres to the established paradigm of using computational methods for molecular design and property prediction. Highlights This preprint presents a novel benchmark

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Large-scale skin metagenomics reveals extensive prevalence, coordination, and functional adaptation of skin microbiome dermotypes across body sites

URL https://www.biorxiv.org/content/10.1101/2025.04.24.650393v2.full.pdf Stage Normal Science Paradigm framing Human Microbiome Project (HMP) Highlights This research expands upon the established paradigm of the Human Microbiome Project by focusing on in-depth characterization of the skin microbiome and introducing the novel concept of "dermotypes". While acknowledging the existing knowledge of site-specific differences in skin microbial composition, the study builds

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A Transient Increase in Cardiomyocyte Protein O-GlcNAcylation Enhances Susceptibility to Pressure Overload-Induced Cardiac Remodeling

URL https://www.biorxiv.org/content/10.1101/2025.06.04.657956v1.full.pdf Stage Normal Science Paradigm framing The preprint operates within the dominant paradigm of metabolic memory in diabetic heart disease, specifically focusing on the role of O-GlcNAcylation. Highlights This research uses established models and methodologies to investigate a specific aspect of metabolic memory within the existing paradigm. The study builds upon prior knowledge and

A Transient Increase in Cardiomyocyte Protein O-GlcNAcylation Enhances Susceptibility to Pressure Overload-Induced Cardiac Remodeling Read More »

Understanding how adolescents experience violence and its perceived impacts on mental health: A qualitative study across 13 countries

URL https://assets-eu.researchsquare.com/files/rs-6822872/v1/a7b11fcd-1a77-4fda-9adb-b5d0edb6de80.pdf?c=1749114878 Stage Normal Science Paradigm framing The preprint operates within the paradigm of social and behavioral sciences, specifically focusing on public health and adolescent psychology. It utilizes established methodologies like qualitative research and thematic analysis, aligning with accepted norms within the field. Highlights This research contributes to the existing body of knowledge on adolescent

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Direct observation of layer skyrmions in twisted WSe2 bilayers

URL https://www.researchsquare.com/article/rs-4652186/v1.pdf?c=1746183939000 Stage Normal Science Paradigm framing Condensed Matter Physics, two-dimensional materials, specifically twisted bilayer WSe2. The dominant paradigm is the study of quantum phenomena arising from topology and correlation in moiré materials. Highlights This preprint presents a direct observation of a layer-skyrmion texture using scanning tunneling microscopy/spectroscopy (STM/STS), applied to twisted WSe2 bilayers. This

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