Preprint Watch

Who Owns the Knowledge? Copyright, GenAI, and the Future of Academic Publishing

URL https://arxiv.org/pdf/2511.21755.pdf Stage Model Crisis Paradigm framing The paper operates within the paradigm of intellectual property and scholarly communication, which is governed by established copyright laws, licensing frameworks like Creative Commons, and academic norms of attribution. This paradigm is being challenged by the anomaly of generative AI (GenAI), which uses vast amounts of copyrighted academic […]

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Modeling the Global Citation Network using the Scalable Agent-based Simulator for Citation Analysis with Recency-emphasized Sampling (SASCA-ReS)

URL https://zenodo.org/records/17789558/files/tbp.pdf Stage Model Drift Paradigm framing The paper operates within the scientometrics paradigm, specifically focusing on the computational modeling of citation network dynamics. This paradigm seeks to explain the large-scale structure and evolution of scientific literature through generative models based on principles like preferential attachment, recency, and fitness. The research puzzle is to create

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Iron deficiency drives metabolic adaptation of red pulp macrophages via ferroportin-SYK signaling and BCAA catabolism to enhance erythrophagocytosis

URL https://www.biorxiv.org/content/10.1101/2025.06.13.659526v3.full.pdf Stage Model Drift Paradigm framing The research is situated within the established paradigms of cellular iron homeostasis, macrophage biology, and efferocytosis. The prevailing model posits that systemic iron levels are controlled by the hepcidin-ferroportin axis and that macrophages undergo specific metabolic reprogramming to clear aged cells. This paper investigates the adaptive response of

Iron deficiency drives metabolic adaptation of red pulp macrophages via ferroportin-SYK signaling and BCAA catabolism to enhance erythrophagocytosis Read More »

Geographical targeting of active case finding for tuberculosis in Pakistan using artificial intelligence software (SPOT-TB): a pragmatic stepped wedge cluster randomized control trial

URL https://www.medrxiv.org/content/10.64898/2026.05.20.26348577v1 Stage Normal Science Paradigm framing The paper operates within the established paradigm of tuberculosis control, specifically applying and evaluating an artificial intelligence tool within existing public health frameworks for active case finding. Highlights This paper represents an exemplary case of normal science. It rigorously tests and evaluates a novel technological solution (SPOT-TB) within

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Farms, Findings, and False Causation: A Systematic Review of Allergy Prevalence

URL https://www.researchsquare.com/article/rs-7981632/v1.pdf Stage Model Crisis Paradigm framing The dominant paradigm in allergy epidemiology is the "farm effect," which posits that exposure to farming environments provides a protective effect against allergies. This has led to research aimed at identifying specific environmental or microbial factors responsible for this protection. This preprint challenges this paradigm by proposing an

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Environmental protection areas in freshwater: remote sensing data and species diversity in large South American reservoirs

URL https://www.researchsquare.com/article/rs-7741491/v1.pdf Stage Normal Science Paradigm framing The paper operates within the established limnological paradigm that links anthropogenic pressures, such as agriculture and urbanization, to freshwater eutrophication. It also employs the methodological paradigm of using satellite-based remote sensing, specifically the Normalized Difference Chlorophyll Index (NDCI) from Sentinel-2A data, as a tool for large-scale environmental monitoring.

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From resource-rich to resource-poor grasslands: A shift in β-diversity assembly mechanisms from biotic control to abiotic dominance

URL https://www.researchsquare.com/article/rs-7763128/v1.pdf Stage Normal Science Paradigm framing This research is situated within the established paradigm of community ecology and biogeography. It specifically draws upon the theoretical frameworks of niche-based community assembly, environmental filtering, and trait-based ecology. The study uses the species-area relationship (SAR) as a core methodological tool to investigate β-diversity, treating the mechanisms that

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Amino acids as molecular linchpins in fundamental prebiotic processes

URL https://assets-eu.researchsquare.com/files/rs-7866707/v1/dfdff923-98e1-4f23-a8e8-3c246bbc2189.pdf Stage Normal Science Paradigm framing The research is situated within the dominant paradigm of origin-of-life studies, which combines the "RNA world" hypothesis and the protocell model. This framework posits that life emerged from self-replicating RNA molecules (information) enclosed within simple, self-assembling membrane compartments (like fatty acid vesicles). This paper explores the interactions between

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What makes a mycoparasite? Similarities between fungi that attack other fungi and fungal and oomycete plant pathogens based on structural homology of their candidate effectors

URL https://www.researchsquare.com/article/rs-7759314/v1.pdf Stage Model Drift Paradigm framing The paper operates within the established paradigm of mycology that defines mycoparasitism as a fungal lifestyle. However, it challenges the paradigm's lack of molecular-level explanation by proposing a new conceptual framework: that the molecular machinery of mycoparasitism (specifically effector proteins) is analogous to that of fungal plant pathogenesis.

What makes a mycoparasite? Similarities between fungi that attack other fungi and fungal and oomycete plant pathogens based on structural homology of their candidate effectors Read More »

Digital identity system using post-quantum cryptographic paradigms

URL https://www.researchsquare.com/article/rs-6608493/v1.pdf Stage Normal Science Paradigm framing The paper operates within the emerging paradigm of Post-Quantum Cryptography (PQC) as a replacement for the classical public-key cryptography paradigm (e.g., RSA, ECC) which is in a state of crisis due to its vulnerability to quantum computers. The work specifically adopts the newly established exemplars from the NIST

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