Preprint Watch

Trajectory of thirst level in critically ill oncology patients: A group-based trajectory model

URL https://assets-eu.researchsquare.com/files/rs-6488220/v1_covered_bf14d4c6-0551-46a0-bc69-380fce1a703d.pdf Stage Normal Science Paradigm framing The paradigm framing is thirst assessment and management in critically ill patients, particularly those in oncology. The dominant paradigm accepts the importance of thirst management and investigates its prevalence, intensity, and related factors in the ICU setting. This study operates within this paradigm by investigating thirst level trajectories

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Exploratory analysis of text duplication in peer-review reveals peer-review fraud and paper mills

URL https://arxiv.org/pdf/2202.03310.pdf Stage Normal Science Paradigm framing Research Integrity and Peer Review Highlights This preprint sits comfortably within the existing paradigm of research integrity. It explores a specific anomaly within the peer-review process—text duplication—and investigates this anomaly using established methods and tools within data science. While the preprint identifies potential misconduct, it doesn't fundamentally challenge

Exploratory analysis of text duplication in peer-review reveals peer-review fraud and paper mills Read More »

Molecular signatures of chronic antibody-mediated rejection in human liver transplants

URL https://www.medrxiv.org/content/10.1101/2024.02.08.24302515v3.full.pdf Stage Normal Science Paradigm framing The preprint operates within the dominant paradigm of transplant immunology, which recognizes chronic antibody-mediated rejection (cABMR) as a significant factor in liver transplant outcomes. Highlights This research refines the existing understanding of cABMR by providing a detailed molecular characterization. It identifies specific gene expression patterns associated with cABMR,

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Cost of institutional incentives for promoting cooperation in 2×2 games and collective risk games

URL https://arxiv.org/pdf/2506.02968.pdf Stage Normal Science Paradigm framing Evolutionary Game Theory, Institutional Economics, Cooperation Theory Highlights This preprint operates within the established paradigm of evolutionary game theory, specifically focusing on the well-defined problem of promoting cooperation through institutional incentives. The study explores established models like the Prisoner's Dilemma, Stag Hunt, and Collective Risk Game, utilizing standard

Cost of institutional incentives for promoting cooperation in 2×2 games and collective risk games Read More »

New level density parameter beyond Egidy-Bucurescu’s systematics

URL https://arxiv.org/pdf/2506.02322.pdf Stage Normal Science Paradigm framing Nuclear level density (NLD) within the back-shifted Fermi gas (BSFG) model of nuclear structure. Highlights This preprint focuses on refining existing methodologies for calculating level density parameters (LDPs) within the established BSFG model. The authors compile and analyze experimental data, comparing various existing parameterizations and proposing refined fits.

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Evolution of Wormholes under f(R, T) Theory, the Karmarkar Condition and the Casimir Energy

URL https://arxiv.org/pdf/2506.02074.pdf Stage Model Drift Paradigm framing The preprint operates within the established paradigm of Einstein's General Relativity, specifically focusing on the sub-paradigm of wormhole physics. It also engages with the extended paradigm of modified gravity, represented by f(R,T) theory. Highlights This preprint explores wormhole solutions within the f(R,T) gravity theory, a modification of Einstein's

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Exploring the use of Virtual Reality to enhance rapid decompression from occupational stress during short wellness breaks for content moderators

URL https://assets-eu.researchsquare.com/files/rs-5684444/v1_covered_6871fded-8bc3-44c1-a101-5f10e11abdc8.pdf Stage Normal Science Paradigm framing Psychology, Occupational Health, Human-Computer Interaction Highlights This preprint investigates the application of Virtual Reality (VR) for stress reduction in a specific occupational group (content moderators). While the study did not demonstrate significant changes in long-term, trait-based anxiety or occupational stress, it did show reductions in short-term, state-based stress

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Translation-specific disruption of Col1a1 expression in multiple models of Spinal Muscular Atrophy can be rescued by Risdiplam.

URL https://www.biorxiv.org/content/10.1101/2025.06.03.657600v1.full.pdf Stage Normal Science Paradigm framing The preprint operates within the dominant paradigm of molecular biology and genetics as applied to understanding and treating Spinal Muscular Atrophy (SMA). This paradigm emphasizes the role of SMN protein deficiency as the central cause of SMA and focuses on therapies that increase SMN levels. Highlights This preprint

Translation-specific disruption of Col1a1 expression in multiple models of Spinal Muscular Atrophy can be rescued by Risdiplam. Read More »

Behavioral plasticity and the valence of indirect interactions

URL https://www.biorxiv.org/content/10.1101/2024.08.15.608151v2.full.pdf Stage Model Drift Paradigm framing The preprint operates within the paradigm of predator-prey interactions and community ecology, specifically focusing on how individual behavior can influence population dynamics and species interactions. Highlights This preprint presents a model refinement of apparent competition by incorporating behavioral plasticity, specifically hiding behavior in prey species. The core paradigm

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When does rebleeding occur in subarachnoid hemorrhage? Revisiting rebleeding cases with a focus on blood pressure

URL https://www.medrxiv.org/content/10.1101/2025.05.23.25328264v1.full.pdf Stage Normal Science Paradigm framing The paradigm framing is the prevention and management of rebleeding in patients with subarachnoid hemorrhage (SAH), a critical condition with high mortality and morbidity rates. The study operates within the existing paradigm of early intervention and blood pressure management in SAH. Highlights This research firmly falls within the

When does rebleeding occur in subarachnoid hemorrhage? Revisiting rebleeding cases with a focus on blood pressure Read More »