Preprint Watch

Sentiment Simulation using Generative AI Agents

Leave a Comment / arXiv, Model Revolution /

URL https://arxiv.org/pdf/2505.22125.pdf Stage Model Revolution Paradigm framing The preprint challenges the existing paradigm of sentiment analysis as retrospective classification based on surface-level linguistic features. It proposes a shift towards prospective and dynamic sentiment simulation grounded in psychological principles, utilizing generative AI agents embodied with psychographic profiles. Highlights This preprint presents a compelling case for a […]

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Dust Budget Crisis in Little Red Dots

Leave a Comment / arXiv, Model Crisis, Model Drift /

URL https://arxiv.org/pdf/2505.22600.pdf Stage Model Drift / Model Crisis Paradigm framing The preprint challenges the prevailing paradigm that Little Red Dots (LRDs) are heavily dust-reddened Active Galactic Nuclei (AGNs). The current paradigm, based on their red spectra, suggests high extinction levels (Av ~ 3). Highlights The authors present evidence suggesting a “dust budget crisis,” where the

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Geospatial Foundation Models to Enable Progress on Sustainable Development Goals

Leave a Comment / arXiv, Normal Science /

URL https://arxiv.org/pdf/2505.24528.pdf Stage Normal Science Paradigm framing Artificial Intelligence, Earth Observation, Sustainable Development Goals, Foundation Models Highlights The preprint focuses on evaluating and benchmarking existing Foundation Models (FMs) within the established paradigm of applying AI to Earth Observation (EO) data for addressing Sustainable Development Goals (SDGs). It introduces SustainFM, a novel benchmarking framework, and presents

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Interictal Epileptiform Discharge Detection Using Probabilistic Diffusion Models and AUPRC Maximization

Leave a Comment / medRxiv, Normal Science /

URL https://www.medrxiv.org/content/10.1101/2025.05.23.25328198v2.full.pdf Stage Normal Science Paradigm framing The paradigm is automated interictal epileptiform discharge (IED) detection in electroencephalography (EEG) using artificial intelligence. The current model accepts that deep learning is a highly effective method but notes limitations due to class imbalance in datasets and a focus on metrics that don’t directly translate to clinical utility.

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Epigenetic mediation may explain intergenerational associations between maternal lifestyle and birth weight of offsprings – Findings from the NorthPop prospective birth cohort

Leave a Comment / medRxiv, Normal Science /

URL https://www.medrxiv.org/content/10.1101/2025.06.01.25328723v1.full.pdf Stage Normal Science Paradigm framing The preprint operates within the dominant paradigm of DOHaD (Developmental Origins of Health and Disease), specifically focusing on the role of epigenetics in mediating the relationship between maternal lifestyle during pregnancy and offspring birth weight. It utilizes established methodologies of statistical analysis and DNA methylation assessment, working within

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Green Synthesis of Cuo Nanoparticles Using Gloriosa Superba L. Extract by Phytochemical Analysis and Antimicrobial Applications

Leave a Comment / Normal Science, Research Square /

URL https://assets-eu.researchsquare.com/files/rs-6764786/v1/2dc5cde3-f6c7-4b77-b079-dcfd5e9b9fd2.pdf?c=1748866802.pdf Stage Normal Science Paradigm framing Nanotechnology, Green Chemistry, Material Science, Microbiology. Highlights The preprint investigates the green synthesis of CuO nanoparticles using Gloriosa superba L. extract. This research falls under the normal science stage because it operates within the established paradigm of nanotechnology and green chemistry. It explores a specific application of existing

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Disentangling objects′ contextual associations from perceptual and conceptual attributes using time-resolved neural decoding

Leave a Comment / bioRxiv, Normal Science /

URL https://www.biorxiv.org/content/10.1101/2025.05.29.656895v2.full.pdf Stage Normal Science Paradigm framing The preprint operates within the established paradigm of cognitive neuroscience, specifically focusing on visual object recognition and its neural underpinnings. It adheres to the dominant assumption that object knowledge is represented in a distributed and dynamic manner in the brain, with perceptual and conceptual features playing distinct roles.

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Slow-Timescale Regulation of Dopamine Release and Mating Drive over Days

Leave a Comment / bioRxiv, Normal Science /

URL https://www.biorxiv.org/content/10.1101/2025.05.29.656898v1.full.pdf Stage Normal Science Paradigm framing The preprint operates within the established paradigm of neuroendocrine regulation of behavior, specifically focusing on the role of dopamine in modulating mating drive. Highlights This research utilizes established experimental techniques like fluorescence lifetime imaging microscopy, electrophysiology, and optogenetics to investigate a specific aspect of dopamine’s function in mating

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Genetic signatures of bipolar disorder course specifiers

Leave a Comment / medRxiv, Normal Science /

URL https://www.medrxiv.org/content/10.1101/2025.05.17.25327825v1.full.pdf Stage Normal Science Paradigm framing The preprint operates within the dominant paradigm of psychiatric genetics, which emphasizes the role of genetic factors in the development and manifestation of mental disorders. It also adheres to the dimensional approach to psychopathology, viewing mental illness as existing on a spectrum rather than as discrete categories. Highlights

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Change point based dynamic functional connectivity estimation outperforms sliding window and static estimation for classification of early mild cognitive impairment in resting-state fMRI

Leave a Comment / bioRxiv, Normal Science /

URL https://www.biorxiv.org/content/10.1101/2025.05.16.654552v2.full.pdf Stage Normal Science Paradigm framing The preprint operates within the dominant paradigm of using functional magnetic resonance imaging (fMRI) and network neuroscience to study brain function and disorders. Specifically, it focuses on the sub-paradigm of dynamic functional connectivity (DFC) analysis, which has gained traction in recent years as a way to capture the

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