Synthetic mRNA Vaccines and Transcriptomic Dysregulation: Evidence from New-Onset Adverse Events and Cancers Post-Vaccination

The preprint operates within the dominant paradigm of molecular biology and immunology, specifically focusing on transcriptomics and immune responses related to mRNA vaccines.

This preprint presents findings that challenge certain aspects of the current understanding of mRNA vaccine safety, potentially indicating a model drift. While not proposing a complete paradigm shift, the study highlights significant transcriptomic dysregulation in individuals experiencing adverse events or new-onset cancers post-mRNA vaccination. These findings raise questions about the long-term effects of these vaccines and suggest potential avenues for further research into their safety profile and host response variability. The study's limitations, particularly the small sample size of the affected cohorts, necessitate further investigation to confirm these findings and solidify their implications within the existing paradigm. Therefore, a classification of "Model Drift" appears most appropriate, as it acknowledges the potential for these findings to refine the current model without necessarily overturning it. A secondary classification of "Model Crisis" could also be considered if the findings are replicated in larger studies and gain wider acceptance within the scientific community, potentially leading to a reevaluation of the current assumptions regarding mRNA vaccine safety.