Research Square

What makes a mycoparasite? Similarities between fungi that attack other fungi and fungal and oomycete plant pathogens based on structural homology of their candidate effectors

Leave a Comment / Model Revolution, Research Square /

URL https://www.researchsquare.com/article/rs-7759314/v1.pdf Stage Model Revolution Paradigm framing The paper is situated within mycology and microbial ecology. The prevailing paradigm for understanding mycoparasitism (fungi parasitizing other fungi) has been largely descriptive, relying on empirical observation and ecological classification. This research introduces a new conceptual model by framing mycoparasitism within the well-established molecular paradigm of plant-pathogen interactions. […]

What makes a mycoparasite? Similarities between fungi that attack other fungi and fungal and oomycete plant pathogens based on structural homology of their candidate effectors Read More »

Hybrid Switched-capacitor Three-phase Direct AC-AC Converter with Adjustable Output Voltage

Leave a Comment / Normal Science, Research Square /

URL https://assets-eu.researchsquare.com/files/rs-7760201/v1_covered_5cfbd94a-81f9-4cab-9358-80e228b82f0c.pdf Stage Normal Science Paradigm framing The research is situated within the power electronics field, specifically addressing the paradigm of direct AC-AC power conversion using Switched-Capacitor (SC) converter topologies. This paradigm aims to develop compact, efficient, and transformer-less voltage converters. The paper works to extend this paradigm by solving the puzzle of achieving adjustable

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Room-Temperature Superconductivity at 298 K in Ternary La-Sc-H System at High-pressure Conditions

Leave a Comment / Model Revolution, Research Square /

URL https://assets-eu.researchsquare.com/files/rs-7755852/v1/0c8d2926-46f8-41bb-bd8b-ca9652f0b42e.pdf Stage Model Revolution Paradigm framing The research operates within the established paradigm of condensed matter physics that seeks high-temperature superconductivity in hydrogen-rich materials under extreme pressure. This paradigm posits that hydrogen-based clathrate structures can achieve high critical temperatures (Tc). This paper extends the paradigm from binary (e.g., LaH10) to ternary systems (La-Sc-H), proposing

Room-Temperature Superconductivity at 298 K in Ternary La-Sc-H System at High-pressure Conditions Read More »

Global human myeloid replacement with peripheral progenitors induces interferonopathy and neurodegeneration

Leave a Comment / Model Crisis, Research Square /

URL https://assets-eu.researchsquare.com/files/rs-7762822/v1/992f5429-50f2-4255-9eea-73dfc72d2753.pdf Stage Model Crisis Paradigm framing The research addresses the paradigm in neuroimmunology and regenerative medicine which posits that replacing dysfunctional brain microglia with healthy, peripherally-derived hematopoietic stem cells (HSCs) is a viable therapeutic strategy for neurodegenerative diseases. This prevailing model is largely founded on evidence from murine studies suggesting that such replacement is

Global human myeloid replacement with peripheral progenitors induces interferonopathy and neurodegeneration Read More »

Predictive Emotional Selfhood in Articial Minds (PESAM): A Unied and Synergistic Variational Framework

Leave a Comment / Model Drift, Research Square /

URL https://assets-eu.researchsquare.com/files/rs-7713015/v1_covered_edbb151e-5647-4e84-9b22-f21605513872.pdf Stage Model Drift Paradigm framing The preprint operates within the paradigm of the Active Inference framework and the Free Energy Principle in computational neuroscience and artificial intelligence. This paradigm posits that intelligent agents perceive, act, and learn by continuously minimizing prediction error (or surprise) about their sensory inputs. The paper specifically addresses the

Predictive Emotional Selfhood in Articial Minds (PESAM): A Unied and Synergistic Variational Framework Read More »

Engineering ZnO/g-C₃N₄ Heterostructures for Enhanced Photocatalytic Performance under Solar Irradiation

Leave a Comment / Normal Science, Research Square /

URL https://assets-eu.researchsquare.com/files/rs-7502748/v1/c55f5e4f-94a9-40c5-a0f3-36ecc04e8cec.pdf Stage Normal Science Paradigm framing The preprint operates within the established paradigm of photocatalysis for environmental remediation. This paradigm accepts that semiconductor materials can be used to degrade organic pollutants using solar energy. The research aims to improve the efficiency of this process by optimizing existing materials and methods. Highlights This research focuses

Engineering ZnO/g-C₃N₄ Heterostructures for Enhanced Photocatalytic Performance under Solar Irradiation Read More »

Value Creation for Healthcare Ecosystems through Artificial Intelligence Applied to Physician-to-Physician Communication: A Systematic Review

Leave a Comment / Normal Science, Research Square /

URL https://link.springer.com/content/pdf/10.1007/s11063-025-11725-1.pdf Stage Normal Science Paradigm framing Artificial intelligence, natural language processing, and large language models in healthcare. Highlights This systematic review investigates the application of AI to physician-to-physician communication within the existing paradigm of AI in healthcare. It explores the potential of AI to augment physicians' capabilities, particularly in decision-making and knowledge sharing, without

Value Creation for Healthcare Ecosystems through Artificial Intelligence Applied to Physician-to-Physician Communication: A Systematic Review Read More »

AI in Universities: The Good, the Bot, and the Ugly Truths

Leave a Comment / Model Drift, Research Square /

URL https://www.researchsquare.com/article/rs-6883202/v1.pdf Stage Model Drift Paradigm framing The paradigm of the preprint revolves around the integration of Artificial Intelligence (AI) in higher education, specifically focusing on its impact on teaching, learning, and administrative functions. This encompasses the shift towards personalized learning, enhanced efficiency, and improved campus management through the use of AI-powered tools. Highlights The

AI in Universities: The Good, the Bot, and the Ugly Truths Read More »

Understanding how adolescents experience violence and its perceived impacts on mental health: A qualitative study across 13 countries

Leave a Comment / Normal Science, Research Square /

URL https://www.researchsquare.com/article/rs-6822872/v1.pdf?c=1749129278000 Stage Normal Science Paradigm framing The preprint operates within the dominant paradigm of social and behavioral sciences, specifically focusing on the well-established link between violence exposure and mental health outcomes in adolescents. It also acknowledges the socio-ecological model as a framework for understanding violence. Highlights This research firmly falls within the 'Normal Science'

Understanding how adolescents experience violence and its perceived impacts on mental health: A qualitative study across 13 countries Read More »

The largest diamonds are hosted in iron-rich substrate accreted at the base of the lithosphere

Leave a Comment / Normal Science, Research Square /

URL https://assets-eu.researchsquare.com/files/rs-6808081/v1/47d51c46-671e-47e9-afe4-f355d0e1744a.pdf Stage Normal Science Paradigm framing Diamond formation; Kimberlite magma interaction with deep lithospheric substrates Highlights This preprint investigates the origin of CLIPPIR diamonds, large and rare diamonds exhibiting unique characteristics. The authors explore the association between these diamonds and the composition of their host kimberlites, particularly focusing on olivine. Their findings demonstrate a

The largest diamonds are hosted in iron-rich substrate accreted at the base of the lithosphere Read More »