Research Square

Room-Temperature Superconductivity at 298 K in Ternary La-Sc-H System at High-pressure Conditions

Leave a Comment / Model Revolution, Research Square /

URL https://assets-eu.researchsquare.com/files/rs-7755852/v1/0c8d2926-46f8-41bb-bd8b-ca9652f0b42e.pdf Stage Model Revolution Paradigm framing The research operates within the established paradigm of condensed matter physics that seeks high-temperature superconductivity in hydrogen-rich materials under extreme pressure. This paradigm posits that hydrogen-based clathrate structures can achieve high critical temperatures (Tc). This paper extends the paradigm from binary (e.g., LaH10) to ternary systems (La-Sc-H), proposing […]

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Global human myeloid replacement with peripheral progenitors induces interferonopathy and neurodegeneration

Leave a Comment / Model Crisis, Research Square /

URL https://assets-eu.researchsquare.com/files/rs-7762822/v1/992f5429-50f2-4255-9eea-73dfc72d2753.pdf Stage Model Crisis Paradigm framing The research addresses the paradigm in neuroimmunology and regenerative medicine which posits that replacing dysfunctional brain microglia with healthy, peripherally-derived hematopoietic stem cells (HSCs) is a viable therapeutic strategy for neurodegenerative diseases. This prevailing model is largely founded on evidence from murine studies suggesting that such replacement is

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Predictive Emotional Selfhood in Articial Minds (PESAM): A Unied and Synergistic Variational Framework

Leave a Comment / Model Drift, Research Square /

URL https://assets-eu.researchsquare.com/files/rs-7713015/v1_covered_edbb151e-5647-4e84-9b22-f21605513872.pdf Stage Model Drift Paradigm framing The preprint operates within the paradigm of the Active Inference framework and the Free Energy Principle in computational neuroscience and artificial intelligence. This paradigm posits that intelligent agents perceive, act, and learn by continuously minimizing prediction error (or surprise) about their sensory inputs. The paper specifically addresses the

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Engineering ZnO/g-C₃N₄ Heterostructures for Enhanced Photocatalytic Performance under Solar Irradiation

Leave a Comment / Normal Science, Research Square /

URL https://assets-eu.researchsquare.com/files/rs-7502748/v1/c55f5e4f-94a9-40c5-a0f3-36ecc04e8cec.pdf Stage Normal Science Paradigm framing The preprint operates within the established paradigm of photocatalysis for environmental remediation. This paradigm accepts that semiconductor materials can be used to degrade organic pollutants using solar energy. The research aims to improve the efficiency of this process by optimizing existing materials and methods. Highlights This research focuses

Engineering ZnO/g-C₃N₄ Heterostructures for Enhanced Photocatalytic Performance under Solar Irradiation Read More »

Value Creation for Healthcare Ecosystems through Artificial Intelligence Applied to Physician-to-Physician Communication: A Systematic Review

Leave a Comment / Normal Science, Research Square /

URL https://link.springer.com/content/pdf/10.1007/s11063-025-11725-1.pdf Stage Normal Science Paradigm framing Artificial intelligence, natural language processing, and large language models in healthcare. Highlights This systematic review investigates the application of AI to physician-to-physician communication within the existing paradigm of AI in healthcare. It explores the potential of AI to augment physicians' capabilities, particularly in decision-making and knowledge sharing, without

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AI in Universities: The Good, the Bot, and the Ugly Truths

Leave a Comment / Model Drift, Research Square /

URL https://www.researchsquare.com/article/rs-6883202/v1.pdf Stage Model Drift Paradigm framing The paradigm of the preprint revolves around the integration of Artificial Intelligence (AI) in higher education, specifically focusing on its impact on teaching, learning, and administrative functions. This encompasses the shift towards personalized learning, enhanced efficiency, and improved campus management through the use of AI-powered tools. Highlights The

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Understanding how adolescents experience violence and its perceived impacts on mental health: A qualitative study across 13 countries

Leave a Comment / Normal Science, Research Square /

URL https://www.researchsquare.com/article/rs-6822872/v1.pdf?c=1749129278000 Stage Normal Science Paradigm framing The preprint operates within the dominant paradigm of social and behavioral sciences, specifically focusing on the well-established link between violence exposure and mental health outcomes in adolescents. It also acknowledges the socio-ecological model as a framework for understanding violence. Highlights This research firmly falls within the 'Normal Science'

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The largest diamonds are hosted in iron-rich substrate accreted at the base of the lithosphere

Leave a Comment / Normal Science, Research Square /

URL https://assets-eu.researchsquare.com/files/rs-6808081/v1/47d51c46-671e-47e9-afe4-f355d0e1744a.pdf Stage Normal Science Paradigm framing Diamond formation; Kimberlite magma interaction with deep lithospheric substrates Highlights This preprint investigates the origin of CLIPPIR diamonds, large and rare diamonds exhibiting unique characteristics. The authors explore the association between these diamonds and the composition of their host kimberlites, particularly focusing on olivine. Their findings demonstrate a

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Factor H related 2 levels dictate FHR dimer composition

Leave a Comment / Normal Science, Research Square /

URL https://www.researchsquare.com/article/rs-6130401/v1.pdf Stage Normal Science Paradigm framing The preprint operates within the established paradigm of complement biology, specifically focusing on the role of Factor H and Factor H-Related proteins in regulating the alternative pathway of complement activation. Highlights This preprint focuses on refining the understanding of the dynamic interactions and dimerization of FHR proteins, particularly

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Transcriptional landscape of canine hematopoiesis and cross-species comparisons revealed by single-cell RNA sequencing

Leave a Comment / Normal Science, Research Square /

URL https://www.researchsquare.com/article/rs-6299609/v1.pdf Stage Normal Science Paradigm framing The preprint operates within the dominant paradigm of molecular biology and genomics, specifically focusing on single-cell RNA sequencing as a tool to understand cellular differentiation and lineage commitment. It also adheres to the established paradigm of using model organisms (dogs) to study human diseases. Highlights This research utilizes

Transcriptional landscape of canine hematopoiesis and cross-species comparisons revealed by single-cell RNA sequencing Read More »