A Hypothalamus centered Pathogenesis of Heat Stroke Deaths- A Postmortem-Based Human Study

The preprint operates within the dominant paradigm of heat stroke pathophysiology, which emphasizes the role of thermoregulatory dysfunction and multi-organ failure.

This research reinforces existing understanding by focusing on the anterior hypothalamus's specific role in heat stroke deaths. The study's methodology, involving post-mortem examination and histological analysis, aligns with standard practices in forensic medicine. While the study proposes a "hypothalamus-centered" view, it doesn't fundamentally challenge the existing paradigm. It contributes to a more granular understanding within the current framework, making it a clear example of normal science as it seeks to refine and extend existing knowledge within the accepted paradigm.